BDBM416662 3-allyl 7-methyl 8-hydroxy-5-oxo-4,5-dihydro-1H-chromeno[3,4-c]pyridine-3, 7(2H)-dicarboxylate::US10323013, Compound 41

SMILES COC(=O)C1C2OC(=O)C3=C(CCN(C3)C(=O)OCC=C)C2=CC=C1O

InChI Key InChIKey=NICNYONSCVTLFP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 416662   

TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM416662(3-allyl 7-methyl 8-hydroxy-5-oxo-4,5-dihydro-1H-ch...)
Affinity DataIC50:  5.64E+3nMAssay Description:All compounds were evaluated by FRET-suppression assay in side-by-side experiments using 21b as a control inhibitor (Table 2). Protection of the alde...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent