BDBM426686 1-(3-(2-amino-6-(4-phenoxyphenyl)quinazolin- 8-yl)piperidin-1-yl)prop-2-en-1-one::US10544106, Compound C028::US11208388, Example 53

SMILES Nc1ncc2cc(cc(C3CCCN(C3)C(=O)C=C)c2n1)-c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=NVTZEJGWZZVPKB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 426686   

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426686(1-(3-(2-amino-6-(4-phenoxyphenyl)quinazolin- 8-yl)...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426686(1-(3-(2-amino-6-(4-phenoxyphenyl)quinazolin- 8-yl)...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent