BDBM426742 4-(8-(1-acryloylpyrrolidin-3-yl)-4-amino- imidazo[1,5-a][1,3,5]triazin-6-yl)-N-(4- cyclopropylpyridin-2-yl)benzamide::US10544106, Compound C199::US11208388, Example 201

SMILES Nc1ncnc2c(nc(-c3ccc(cc3)C(=O)Nc3cc(ccn3)C3CC3)n12)C1CCN(C1)C(=O)C=C

InChI Key InChIKey=NFSSGMNLADBWAW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 426742   

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426742(4-(8-(1-acryloylpyrrolidin-3-yl)-4-amino- imidazo[...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426742(4-(8-(1-acryloylpyrrolidin-3-yl)-4-amino- imidazo[...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent