BDBM432117 (S)-2-(tert-butoxy)-2-(4-(4,4-dimethylpiperidin-1-yl)-5-(2-(6- methoxybenzo[d]thiazol-2-yl)-1,2,3,4-tetrahydroisoquinolin-6-yl)- 2,6-dimethylpyridin-3-yl)acetic acid::US10577353, Compound 12

SMILES COc1ccc2nc(sc2c1)N1CCc2cc(ccc2C1)-c1c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c1N1CCC(C)(C)CC1

InChI Key InChIKey=YVKLBBSNJLNFBQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 432117   

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432117(US10577353, Compound 12 | (S)-2-(tert-butoxy)-2-(4...)
Affinity DataEC50:  4nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent