BDBM433662 5-Chloro-2-[1-(1-ethyl-1H-pyrazole-4-carbonyl)-3-methoxypiperidin-3-yl]-3-methylpyridine::US10562882, Example 40

SMILES CCn1cc(cn1)C(=O)N1CCCC(C1)(OC)c1ncc(Cl)cc1C

InChI Key InChIKey=UKAQXPHSQDZUQL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433662   

TargetProkineticin receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM433662(5-Chloro-2-[1-(1-ethyl-1H-pyrazole-4-carbonyl)-3-m...)
Affinity DataIC50:  3.41E+3nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent