BDBM435516 (2R,3S,4R,5R)-5-(4-amino-7H- pyrrolo[2,3-d]pyrimidin-7-yl)-2-(((2- aminoquinolin-7-yl)oxy)methyl)-3- (trifluoromethyl)tetrahydrofuran-3,4-diol::US10570140, Example 2::US11078205, Example 2::US11208416, Example 2
SMILES Nc1ccc2ccc(OC[C@H]3O[C@H]([C@H](O)[C@@]3(O)C(F)(F)F)n3ccc4c(N)ncnc34)cc2n1
InChI Key InChIKey=RPTKDLSRYWBUPV-HIBPSGHXSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 435516
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics
US Patent
Prelude Therapeutics
US Patent
Affinity DataIC50: 1.90nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics
US Patent
Prelude Therapeutics
US Patent
Affinity DataIC50: 1.90nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair