BDBM439358 6-amino-N-[dimethyl(oxido)-lambda4- sulfanylidene]-5-{5-[(3-methyl- 2-furoyl)amino]-1-benzothien-2- yl}nicotinamide::US10633373, Example 33

SMILES Cc1ccoc1C(=O)NC(=O)Nc1ccc2sc(cc2c1)-c1cc(cnc1N)C(=O)N=S(C)(C)=O

InChI Key InChIKey=RTWGOFACILALHD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 439358   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM439358(6-amino-N-[dimethyl(oxido)-lambda4- sulfanylidene]...)
Affinity DataIC50:  457nMAssay Description:PDGFRβ: Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM439358(6-amino-N-[dimethyl(oxido)-lambda4- sulfanylidene]...)
Affinity DataIC50:  17nMAssay Description:VEGFR2: Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent