BDBM454076 US10730863, Example 546

SMILES CCc1cc(C(O)=O)c2ncc(C#CC34CCC(CC3)(CC4)OCc3c(onc3-c3c(Cl)cncc3Cl)C3CC3)n2c1

InChI Key InChIKey=CTQGXEMFWKWLOG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 454076   

TargetBile acid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM454076(US10730863, Example 546)
Affinity DataEC50:  7nMAssay Description:A Gal4-hFXR fusion construct reporter system was used as the primary assay to characterize compound activity. A construct including 5 copies of the G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent