BDBM459196 US10759799, Compound 64

SMILES O=C1NC2CCC(CC2)NCc2cncc(c2)-c2ccc3[nH]nc(-c4nc5c1cccc5[nH]4)c3c2

InChI Key InChIKey=MEVAYWIJMYMJMW-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 459196   

TargetGlycogen synthase kinase-3 beta(Human)
Samumed

US Patent
LigandPNGBDBM459196(US10759799, Compound 64)
Affinity DataEC50:  88nMAssay Description:The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies a Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
US Patent

LigandPNGBDBM459196(US10759799, Compound 64)
Affinity DataEC50:  448nMAssay Description:The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies a Divis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
US Patent