BDBM471698 US10822342, Compound 6

SMILES CCN1CCC(C1)n1cc(-c2nc(N)nc3cn(CC)nc23)c2cc(C#CC(C)(C)O)c(F)cc12

InChI Key InChIKey=BVTHRCMTRITCEA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 471698   

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM471698(US10822342, Compound 6)
Affinity DataIC50: 37nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (αscreen) format (Perkin Elmer). All compounds tested were dissolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2021
Entry Details
US Patent