BDBM48011 1-benzyl-5-[(E)-2-nitroethenyl]indole::1-benzyl-5-[(E)-2-nitrovinyl]-1H-indole::1-benzyl-5-[(E)-2-nitrovinyl]indole::5-[(E)-2-nitroethenyl]-1-(phenylmethyl)indole::MLS001198402::SMR000559050::cid_674819

SMILES [O-][N+](=O)\C=C\c1ccc2n(Cc3ccccc3)ccc2c1

InChI Key InChIKey=PWAJOQMAZBVOOC-UHFFFAOYSA-N

Data  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 48011   

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM48011(SMR000559050 | 1-benzyl-5-[(E)-2-nitrovinyl]-1H-in...)
Affinity DataIC50: 1.74E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHeat shock protein HSP 90-alpha(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM48011(SMR000559050 | 1-benzyl-5-[(E)-2-nitrovinyl]-1H-in...)
Affinity DataIC50: 2.98E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2011
Entry Details
PCBioAssay
TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM48011(SMR000559050 | 1-benzyl-5-[(E)-2-nitrovinyl]-1H-in...)
Affinity DataEC50:  5.71E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM48011(SMR000559050 | 1-benzyl-5-[(E)-2-nitrovinyl]-1H-in...)
Affinity DataEC50:  6.15E+3nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2011
Entry Details
PCBioAssay
TargetBcl-2-like protein 11(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM48011(SMR000559050 | 1-benzyl-5-[(E)-2-nitrovinyl]-1H-in...)
Affinity DataEC50:  1.23E+4nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetBeta-lactamase(Pseudomonas aeruginosa)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM48011(SMR000559050 | 1-benzyl-5-[(E)-2-nitrovinyl]-1H-in...)
Affinity DataIC50: 3.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay