BDBM480496 N-(4-cyanophenyl)-4-(6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)piperidine-1-carboxamide trifluoroacetate::US10899764, Example 22

SMILES Fc1cccc2-c3cncn3C(C3CCN(CC3)C(=O)Nc3ccc(cc3)C#N)c12

InChI Key InChIKey=BRXBXCHMZKUIKD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480496   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM480496(N-(4-cyanophenyl)-4-(6-fluoro-5H-imidazo[5,1-a]iso...)
Affinity DataIC50: 56.9nMAssay Description:IDO1: For testing, 24 μL of enzyme (IDO1) was diluted 100 times with 50 mM KPB to 2400 μL. The concentration of the enzyme solution was 2.6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
US Patent