BDBM480522 7-fluoro-5-(1-phenylpiperidin-4-yl)-5H-imidazo[5,1-a]isoindole trifluoroacetate::US10899764, Example 2

SMILES Fc1ccc-2c(c1)C(C1CCN(CC1)c1ccccc1)n1cncc-21

InChI Key InChIKey=KTBGVOLFOJOQHZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480522   

TargetTryptophan 2,3-dioxygenase(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM480522(7-fluoro-5-(1-phenylpiperidin-4-yl)-5H-imidazo[5,1...)
Affinity DataIC50: 215nMAssay Description:TDO: For testing, 24 μL of enzyme (TDO) was diluted 100 times with 50 mM KPB to 2400 μL. The concentration of the enzyme solution was 2.6 n...More data for this Ligand-Target Pair
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Date in BDB:
8/15/2021
Entry Details
US Patent