BDBM484790 US10934302, Example 39

SMILES N[C@@H]1c2ccccc2CC11CCN(CC1)c1cnc2c(n[nH]c2n1)N1CCN(c2cc(ccc12)C#N)C1(CC1)C#N

InChI Key InChIKey=OCILGBMEITZFGI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484790   

TargetSH2B adapter protein 2(Human)
Relay Therapeutics

US Patent
LigandPNGBDBM484790(US10934302, Example 39)
Affinity DataIC50: 50nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
US Patent