BDBM4857 1-(4-Chloroanilino)-4-(4-pyrimidylmethyl)phthalazine::CGP79787 Analog 42::N-(4-chlorophenyl)-4-(pyrimidin-4-ylmethyl)phthalazin-1-amine

SMILES Clc1ccc(Nc2nnc(Cc3ccncn3)c3ccccc23)cc1

InChI Key InChIKey=QGCUYXCPMZGMFQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4857   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM4857(1-(4-Chloroanilino)-4-(4-pyrimidylmethyl)phthalazi...)
Affinity DataIC50:  410nMAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM4857(1-(4-Chloroanilino)-4-(4-pyrimidylmethyl)phthalazi...)
Affinity DataIC50:  760nMpH: 7.5 T: 2°CAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed