BDBM492377 US10975081, Example E62

SMILES COc1nc(cc(n1)-n1ncc2cc(C)c(cc12)[C@H]1CCNC[C@H]1F)N1CCOCC1

InChI Key InChIKey=ZLIORUBNNIJICL-SJLPKXTDSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492377   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM492377(US10975081, Example E62)
Affinity DataIC50:  7.94nMAssay Description:1. A 10 mM test compound was dissolved in 100% DMSO and serially diluted 1 in 4. 100 nL of this dilution series was then added to a 384 well, v botto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent