BDBM494907 US10988463, Example 37::{(1R,5S,6s)-3-[5-cyano-4-(difluoromethyl)-6-(pyrrolidin-1-yl)Pyridin-2-yl]-3-azabicyclo[3.1.0]hex-6-yl}acetic acid

SMILES OC(=O)CC1C2CN(CC12)c1cc(C(F)F)c(C#N)c(n1)N1CCCC1

InChI Key InChIKey=XWDAMMRNAUVXCX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 494907   

TargetKetohexokinase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM494907(US10988463, Example 37 | {(1R,5S,6s)-3-[5-cyano-4-...)
Affinity DataIC50:  58.3nMAssay Description:Assay A, a 384-well format on a Corning 3653 assay plate is used, and monitored by UV-vis spectroscopy in continuous mode at rt. Compounds were prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent