BDBM50010389 CHEMBL3263965

SMILES COc1cc2c(Oc3ccc(NS(=O)(=O)c4cc(ccc4F)-c4ccsc4)cc3F)ccnc2cc1OCCCN1CCN(C)CC1

InChI Key InChIKey=JGBFZYXPJYFPPR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50010389   

TargetEpidermal growth factor receptor(Human)
Vichem Chemie Research

Curated by ChEMBL
LigandPNGBDBM50010389(CHEMBL3263965)
Affinity DataIC50: 572nMAssay Description:Inhibition of recombinant EGFR (unknown origin) using poly-GT peptide as substrate by Transcreener assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Vichem Chemie Research

Curated by ChEMBL
LigandPNGBDBM50010389(CHEMBL3263965)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of recombinant c-MET (unknown origin) using poly-AEKY peptide as substrate after 60 mins by ADPGlo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Vichem Chemie Research

Curated by ChEMBL
LigandPNGBDBM50010389(CHEMBL3263965)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of recombinant INSR (unknown origin) using fluorescent dye-labelled KKSRGDYMTMQIG peptide peptide as substrate after 1 hr by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed