BDBM50011810 CHEMBL3263246

SMILES OC(=O)c1ccc(NC(=O)c2ccccc2NC(=O)c2ccc3ccccc3c2)cc1

InChI Key InChIKey=DTNOBSUPIZLBQI-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50011810   

TargetBile acid receptor(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50011810(CHEMBL3263246)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human FXR expressed in human HeLa cells assessed as transactivation after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50011810(CHEMBL3263246)
Affinity DataEC50:  2.10E+4nMAssay Description:Transactivation of Gal4-tagged PPARgamma ligand binding domain (unknown origin) expressed in COS7 cells measured after overnight incubation by lucife...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50011810(CHEMBL3263246)
Affinity DataEC50:  1.00E+3nMAssay Description:Transactivation of human FXR expressed in human HeLa cells incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed