BDBM50012692 2-tert-Butyl-naphthalen-1-ol::CHEMBL122254

SMILES CC(C)(C)c1ccc2ccccc2c1O

InChI Key InChIKey=PZERHTYUARNDEK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50012692   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50012692(CHEMBL122254 | 2-tert-Butyl-naphthalen-1-ol)
Affinity DataIC50: 180nMAssay Description:Ability to inhibit 5-lipoxygenase by using a crude preparation of the cytosolic enzyme from the rat basophilic leukemia (RBL-1) cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50012692(CHEMBL122254 | 2-tert-Butyl-naphthalen-1-ol)
Affinity DataIC50: 3.70E+4nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase in BSV cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed