BDBM50015369 CHEMBL3264597

SMILES COc1cc2ccc(cc2cc1OC)C(O)(C(C)C)c1c[nH]nn1

InChI Key InChIKey=ZBZKIRAMMFHRIY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50015369   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015369(CHEMBL3264597)
Affinity DataIC50: 180nMAssay Description:Inhibition of rat testicular microsome CYP17 lyase activity using 17alpha-hydroxypregnenolone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015369(CHEMBL3264597)
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant CYP17 lyase activity using 17alpha-hydroxypregnenolone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015369(CHEMBL3264597)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human recombinant CYP17 hydroxylase activity by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015369(CHEMBL3264597)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of human hepatocyte microsome CYP3A4 using testosterone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed