BDBM50037131 (4aR,7S,7aR,12bS)-3-Cyclopropylmethyl-2,3,4,4a,5,6,7,7a-octahydro-1H-8-oxa-3-aza-benzo[d]fluorene-7,9-diol::CHEMBL319236

SMILES O[C@H]1CC[C@H]2CN(CC3CC3)CC[C@]22[C@H]1Oc1c2cccc1O

InChI Key InChIKey=KTXMLKWFHNEBJM-FDARSICLSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50037131   

TargetMu-type opioid receptor(GUINEA PIG)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50037131((4aR,7S,7aR,12bS)-3-Cyclopropylmethyl-2,3,4,4a,5,6...)
Affinity DataKi:  1.40nMAssay Description:In vivo binding affinity against mu opioid receptor was measured by using labeled ligand [3H]-Naloxone (0.5 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50037131((4aR,7S,7aR,12bS)-3-Cyclopropylmethyl-2,3,4,4a,5,6...)
Affinity DataKi:  4.90nMAssay Description:In vivo binding affinity against kappa opioid receptor was measured by using labeled ligand [3H]-ethylketocyclazocine (1 nM) with 500 nM DADLE and 20...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50037131((4aR,7S,7aR,12bS)-3-Cyclopropylmethyl-2,3,4,4a,5,6...)
Affinity DataKi:  15nMAssay Description:In vivo binding affinity against delta Opioid receptor was measured by using labeled ligand [3H]-DADLE (1 nM) with 4 nM sufentanilMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50037131((4aR,7S,7aR,12bS)-3-Cyclopropylmethyl-2,3,4,4a,5,6...)
Affinity DataKi:  580nMAssay Description:In vivo binding affinity against sigma Opioid receptor was measured by using labeled ligand [3H]-SKF- 10,047 (1 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed