BDBM50040350 8-Amino-1,3-bis-cyclopropylmethyl-7-methanesulfonyl-3,7-dihydro-purine-2,6-dione::CHEMBL341866

SMILES CS(=O)(=O)n1c(N)nc2n(CC3CC3)c(=O)n(CC3CC3)c(=O)c12

InChI Key InChIKey=XUCABXWAQNABLW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50040350   

TargetAdenosine receptor A1(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040350(8-Amino-1,3-bis-cyclopropylmethyl-7-methanesulfony...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of adenosine binding to A1 receptor of rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040350(8-Amino-1,3-bis-cyclopropylmethyl-7-methanesulfony...)
Affinity DataIC50: 3.20E+4nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed