BDBM50042518 CHEMBL332092::N-hydroxy-N-[(2-methyl-6-phenyoxy-2H-chromen-3-yl)methyl]urea

SMILES CC1Oc2ccc(Oc3ccccc3)cc2C=C1CN(O)C(N)=O

InChI Key InChIKey=FIGIZBVLAXGLJQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50042518   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50042518(CHEMBL332092 | N-hydroxy-N-[(2-methyl-6-phenyoxy-2...)
Affinity DataIC50:  87nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase by reduction of LTB4 formed in guinea pig polymorphonuclear leukocytes (PMNs).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50042518(CHEMBL332092 | N-hydroxy-N-[(2-methyl-6-phenyoxy-2...)
Affinity DataIC50:  120nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase by reduction of 5-hydroxyeicosatetraenoic acid (5-HETE) formed in guinea pig polymorphonuclear le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed