BDBM50049437 CHEMBL3356474

SMILES C[C@H]1N2C(COc3cc(c(NC4CNC4)cc23)C(F)(F)F)=NNC1=O

InChI Key InChIKey=IYXLXYYJVSGEMN-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50049437   

TargetProtein kinase C theta type(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50049437(CHEMBL3356474)
Affinity DataIC50: 49nMAssay Description:Inhibition of human recombinant PKCtheta expressed in Sf21 cells using Bio-cdc peptide substrate and ATP after 60 mins by time-resolved fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50049437(CHEMBL3356474)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant PKCepsilon expressed in Sf21 cells using Bio-cdc peptide substrate and ATP after 60 mins by time-resolved fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50049437(CHEMBL3356474)
Affinity DataIC50: 470nMAssay Description:Inhibition of human recombinant PKCdelta expressed in Sf21 cells using Bio-cdc peptide substrate and ATP after 60 mins by time-resolved fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50049437(CHEMBL3356474)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human recombinant PKCbeta expressed in Sf21 cells using Bio-cdc peptide substrate and ATP after 60 mins by time-resolved fluorescence i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50049437(CHEMBL3356474)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human recombinant PKCalpha expressed in Sf21 cells using Bio-cdc peptide substrate and ATP after 60 mins by time-resolved fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
TargetProtein kinase C gamma type(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50049437(CHEMBL3356474)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of human recombinant PKCgamma expressed in Sf21 cells using Bio-cdc peptide substrate and ATP after 60 mins by time-resolved fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50049437(CHEMBL3356474)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
TargetProtein kinase C zeta type(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50049437(CHEMBL3356474)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human recombinant PKCzeta expressed in Sf21 cells using Bio-cdc peptide substrate and ATP after 60 mins by time-resolved fluorescence i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed