BDBM50051605 CHEMBL414554::Dynorphin A analogues

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O

InChI Key InChIKey=WAQSKPSRNCKKCL-AVQQMTKPSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50051605   

TargetMu-type opioid receptor(GUINEA PIG)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50051605(CHEMBL414554 | Dynorphin A analogues)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of binding [3H]-DAMGO at Opioid receptor mu 1 of guinea pig brain membrane (GPB) homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50051605(CHEMBL414554 | Dynorphin A analogues)
Affinity DataIC50:  1.30E+4nMAssay Description:Agonistic activity towards Opioid receptor delta 1 was determined by evaluating the inhibitory activity towards electrically stimulated mouse vas def...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50051605(CHEMBL414554 | Dynorphin A analogues)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of binding [3H]U-69,539 at Opioid receptor kappa 1 of guinea pig brain membrane (GPB) homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed