BDBM50052452 1,8-Dihydroxy-10-(3-phenyl-propylsulfanyl)-10H-anthracen-9-one::CHEMBL106990

SMILES Oc1cccc2C(SCCCc3ccccc3)c3cccc(O)c3C(=O)c12

InChI Key InChIKey=DGUPEDMUTXBHMO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50052452   

Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052452(1,8-Dihydroxy-10-(3-phenyl-propylsulfanyl)-10H-ant...)
Affinity DataIC50:  3.00E+4nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50052452(1,8-Dihydroxy-10-(3-phenyl-propylsulfanyl)-10H-ant...)
Affinity DataIC50: >3.00E+4nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed