BDBM50057522 4-[5-(3-Chloro-4-methoxy-5-methyl-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide::CHEMBL29844

SMILES COc1c(C)cc(cc1Cl)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F

InChI Key InChIKey=GSEIVMGTTSORTO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50057522   

TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057522(4-[5-(3-Chloro-4-methoxy-5-methyl-phenyl)-3-triflu...)
Affinity DataIC50: 66nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057522(4-[5-(3-Chloro-4-methoxy-5-methyl-phenyl)-3-triflu...)
Affinity DataIC50: 66nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057522(4-[5-(3-Chloro-4-methoxy-5-methyl-phenyl)-3-triflu...)
Affinity DataIC50: 66.1nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057522(4-[5-(3-Chloro-4-methoxy-5-methyl-phenyl)-3-triflu...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory concentration required to block recombinant human prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed