BDBM50057569 4-[5-(2,4-Dichloro-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide::CHEMBL281978

SMILES NS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc(Cl)cc1Cl)C(F)(F)F

InChI Key InChIKey=VKCVJTXXANYFGD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50057569   

TargetProstaglandin G/H synthase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50057569(4-[5-(2,4-Dichloro-phenyl)-3-trifluoromethyl-pyraz...)
Affinity DataIC50: 56nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50057569(4-[5-(2,4-Dichloro-phenyl)-3-trifluoromethyl-pyraz...)
Affinity DataIC50: 56nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50057569(4-[5-(2,4-Dichloro-phenyl)-3-trifluoromethyl-pyraz...)
Affinity DataIC50: 56.2nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057569(4-[5-(2,4-Dichloro-phenyl)-3-trifluoromethyl-pyraz...)
Affinity DataIC50: 3.12E+4nMAssay Description:In vitro inhibitory concentration required to block recombinant human prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed