BDBM50057616 4-[5-(3-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide::CHEMBL29620

SMILES NS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1cccc(F)c1)C(F)(F)F

InChI Key InChIKey=CPCDNKFXSPUXSE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50057616   

TargetProstaglandin G/H synthase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50057616(4-[5-(3-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1...)
Affinity DataIC50: 7.73E+3nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50057616(4-[5-(3-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1...)
Affinity DataIC50: 7.73E+3nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057616(4-[5-(3-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory concentration required to block recombinant human prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed