BDBM50059120 5,7-Dimethyl-2-p-tolyl-1H-[1,8]naphthyridin-4-one::CHEMBL49330

SMILES Cc1ccc(cc1)-c1cc(O)c2c(C)cc(C)nc2n1

InChI Key InChIKey=JMIJQUSJCPEKAN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059120   

TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059120(5,7-Dimethyl-2-p-tolyl-1H-[1,8]naphthyridin-4-one ...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059120(5,7-Dimethyl-2-p-tolyl-1H-[1,8]naphthyridin-4-one ...)
Affinity DataIC50:  9.80E+3nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed