BDBM50059852 (S)-2-((S)-2-((S)-2-((R)-2-amino-3-mercaptopropylamino)-3-methylbutylamino)-3-phenylpropanamido)-4-(methylthio)butanoic acid::(S)-2-{(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methyl-butylamino]-3-phenyl-propionylamino}-4-methylsulfanyl-butyric acid::CHEMBL91722::N-[2(S)-[2(R)-amino-3-mercaptopropylamino]-3-methylbutyl]-Phe-Met-OH
SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC[C@@H](NC[C@@H](N)CS)C(C)C)C(O)=O
InChI Key InChIKey=QISLMXIYRQCLIR-FUMNGEBKSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50059852
Affinity DataIC50: 21nMAssay Description:Compound was evaluated for concentration that caused 50% inhibition of bovine FarnesyltransferaseMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Compound was evaluated for concentration that caused 50% inhibition of yeast Farnesyltransferase (expressed as a GST fusion protein in E. coli)More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:In vitro inhibiion of bovine farnesyl transferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of bovine FarnesyltransferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Ras processing in v-Ras-transformed cellsMore data for this Ligand-Target Pair