BDBM50060832 CHEMBL3394715::US10696692, Example 11

SMILES O=C(NCc1ccc(cc1)S(=O)(=O)N1CCOCC1)c1cc2ccncc2s1

InChI Key InChIKey=DANBCPVGQGERJP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50060832   

TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM50060832(CHEMBL3394715 | US10696692, Example 11)
Affinity DataIC50:  20.8nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM50060832(CHEMBL3394715 | US10696692, Example 11)
Affinity DataIC50:  21nMAssay Description:Inhibition of human C-terminal His6-tagged NAMPT expressed in Escherichia coli Rosetta(DE3) incubated for 15 mins prior to substrate addition measure...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed