BDBM50063410 1-[4-((S)-3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-piperidin-4-yl-ethanone::CHEMBL167889

SMILES Clc1ccc2[C@H](N3CCN(CC3)C(=O)CC3CCNCC3)c3ncc(Br)cc3CCc2c1

InChI Key InChIKey=VOCBHZWNUHMROR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50063410   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50063410(1-[4-((S)-3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5...)
Affinity DataIC50: 78nMAssay Description:In vitro inhibition of farnesyltransferase farnesylation of the H-ras oncogeneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed