BDBM50065012 1-Benzyl-1-[3-(2H-pyrazol-3-yl)-benzyl]-3-(2,4,6-trimethyl-phenyl)-urea::CHEMBL81651

SMILES Cc1cc(C)c(NC(=O)N(Cc2ccccc2)Cc2cccc(c2)-c2cc[nH]n2)c(C)c1

InChI Key InChIKey=UULJGWKYDXORCV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50065012   

TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50065012(1-Benzyl-1-[3-(2H-pyrazol-3-yl)-benzyl]-3-(2,4,6-t...)
Affinity DataIC50:  21nMAssay Description:In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase (ACAT) in rabbit intestinal microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50065012(1-Benzyl-1-[3-(2H-pyrazol-3-yl)-benzyl]-3-(2,4,6-t...)
Affinity DataIC50:  21nMAssay Description:In vitro inhibitory activity towards ACAT by the displacement of [1-14C]-oleolyl-CoA from the small intestine of cholesterol-fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed