BDBM50065490 CHEMBL3402754

SMILES Cc1cnc(nc1)-c1cccc(Cn2nc(ccc2=O)-c2cc(F)cc(F)c2)c1

InChI Key InChIKey=XWDNKEHWOTTWBY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50065490   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50065490(CHEMBL3402754)
Affinity DataIC50:  40nMAssay Description:Inhibition of GST-His6-tagged recombinant human c-Met kinase domain (956 to 1390) after 60 mins by anoff-chip mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50065490(CHEMBL3402754)
Affinity DataIC50: >1nMAssay Description:Inhibition of c-Met kinase in human A549 cells assessed as inhibition of phosphorylation after 45 mins by electrochemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed