BDBM50076136 (S)-4-Methyl-2-{2-naphthalen-1-yl-4-[(pyridin-2-ylmethyl)-amino]-benzoylamino}-pentanoic acid::CHEMBL282297

SMILES CC(C)C[C@H](NC(=O)c1ccc(NCc2ccccn2)cc1-c1cccc2ccccc12)C(O)=O

InChI Key InChIKey=CXCXBXSZFZAHTG-MHZLTWQESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50076136   

LigandPNGBDBM50076136((S)-4-Methyl-2-{2-naphthalen-1-yl-4-[(pyridin-2-yl...)
Affinity DataIC50:  4.00E+3nMAssay Description:In vitro inhibition of [3H]-GGPP incorporation into H-Ras-CVLL by Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50076136((S)-4-Methyl-2-{2-naphthalen-1-yl-4-[(pyridin-2-yl...)
Affinity DataIC50:  1.00E+5nMAssay Description:In vitro inhibition of [3H]-FPP incorporation into H-Ras-CVLS by Farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed