BDBM50080498 3-{(S)-3-[(7-Methoxy-naphthalene-2-sulfonyl)-thiophen-3-ylmethyl-amino]-2-oxo-pyrrolidin-1-ylmethyl}-benzamidine::CHEMBL119456

SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)N(Cc1ccsc1)[C@H]1CCN(Cc2cccc(c2)C(N)=N)C1=O

InChI Key InChIKey=HNEAWVZXDQKQPL-SANMLTNESA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50080498   

TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50080498(3-{(S)-3-[(7-Methoxy-naphthalene-2-sulfonyl)-thiop...)
Affinity DataKi:  19nMAssay Description:Compound was evaluated for the inhibition of human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50080498(3-{(S)-3-[(7-Methoxy-naphthalene-2-sulfonyl)-thiop...)
Affinity DataKi:  360nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin(Bos taurus)
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Curated by ChEMBL
LigandPNGBDBM50080498(3-{(S)-3-[(7-Methoxy-naphthalene-2-sulfonyl)-thiop...)
Affinity DataKi:  1.08E+3nMAssay Description:Inhibitory activity against bovine pancreatic trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed