BDBM50090855 (2R,3R,4S,5R)-2-(5-Iodo-4-methylsulfanyl-pyrrolo[2,3-d]pyrimidin-7-yl)-5-methyl-tetrahydro-furan-3,4-diol::(2R,3R,4S,5R)-2-(5-iodo-4-(methylthio)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-methyl-tetrahydrofuran-3,4-diol::2-(5-Iodo-4-methylsulfanyl-pyrrolo[2,3-d]pyrimidin-7-yl)-5-methyl-tetrahydro-furan-3,4-diol::CHEMBL95481

SMILES CSc1ncnc2n(cc(I)c12)[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O

InChI Key InChIKey=JEARWOQCLXHXLR-JJNLEZRASA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50090855   

TargetAdenosine kinase(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50090855((2R,3R,4S,5R)-2-(5-Iodo-4-methylsulfanyl-pyrrolo[2...)
Affinity DataIC50:  45nMAssay Description:Inhibition of recombinant human adenosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50090855((2R,3R,4S,5R)-2-(5-Iodo-4-methylsulfanyl-pyrrolo[2...)
Affinity DataIC50:  4.50E+7nMAssay Description:Inhibition of adenosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAdenosine kinase(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50090855((2R,3R,4S,5R)-2-(5-Iodo-4-methylsulfanyl-pyrrolo[2...)
Affinity DataIC50:  44.7nMAssay Description:Concentration required for 50% inhibition of the adenosine kinase (AK) activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50090855((2R,3R,4S,5R)-2-(5-Iodo-4-methylsulfanyl-pyrrolo[2...)
Affinity DataIC50:  45nMAssay Description:Inhibition of human adenosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed