BDBM50095420 5-tert-Butyl-3-[3-(4-chloro-phenyl)-ureido]-thiophene-2-carboxylic acid methyl ester::CHEMBL278737

SMILES COC(=O)c1sc(cc1NC(=O)Nc1ccc(Cl)cc1)C(C)(C)C

InChI Key InChIKey=OQCCZKUFFXQPQV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50095420   

TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095420(5-tert-Butyl-3-[3-(4-chloro-phenyl)-ureido]-thioph...)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095420(5-tert-Butyl-3-[3-(4-chloro-phenyl)-ureido]-thioph...)
Affinity DataIC50:  220nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed