BDBM50096214 CHEMBL3593814
SMILES COc1ccc(CNC(=O)c2cc(cnc2NCc2ccc3OCOc3c2)C#CC(C)(C)NC(C)=O)cc1Cl
InChI Key InChIKey=RNAPDEZSTCEZPS-BMOOVORFSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50096214
Affinity DataIC50: 34nMAssay Description:Antagonist activity at rat ghrelin receptor expressed in CHO cells assessed as blocking of human ghrelin-induced response by FLIPR based intracellula...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Antagonist activity at ghrelin receptor in Sprague-Dawley rat primary pituitary cells assessed as inhibition of ghrelin-induced growth hormone secret...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inverse agonist activity rat ghrelin receptor expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Asubio Pharma
Curated by ChEMBL
Asubio Pharma
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]human ghrelin from human ghrelin receptor expressed in CHO cell membranes incubated for 30 mins by scintillation counting metho...More data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:Displacement of [125I]human ghrelin from rat ghrelin receptor expressed in CHO cell membranes incubated for 30 mins by scintillation counting methodMore data for this Ligand-Target Pair