BDBM50096216 CHEMBL3593636
SMILES [H][C@]12CC[C@]([H])(CC(=C1)c1cnc(NCc3ccc4OCOc4c3)c(c1)C(=O)NCc1ccc(OC)c(Cl)c1)N(C2)C(C)=O
InChI Key InChIKey=AKUZUUGPWSTEGZ-YECYZZSWSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50096216
Affinity DataIC50: 100nMAssay Description:Antagonist activity at rat ghrelin receptor expressed in CHO cells assessed as blocking of human ghrelin-induced response by FLIPR based intracellula...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Antagonist activity at ghrelin receptor in Sprague-Dawley rat primary pituitary cells assessed as inhibition of ghrelin-induced growth hormone secret...More data for this Ligand-Target Pair
Affinity DataIC50: 9.80nMAssay Description:Inverse agonist activity rat ghrelin receptor expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Asubio Pharma
Curated by ChEMBL
Asubio Pharma
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Displacement of [125I]human ghrelin from human ghrelin receptor expressed in CHO cell membranes incubated for 30 mins by scintillation counting metho...More data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Displacement of [125I]human ghrelin from rat ghrelin receptor expressed in CHO cell membranes incubated for 30 mins by scintillation counting methodMore data for this Ligand-Target Pair