BDBM50105566 6-(3-Nitro-phenyl)-3H-benzothiazol-2-one::CHEMBL315445

SMILES [O-][N+](=O)c1cccc(c1)-c1ccc2[n-]c(=[OH+])sc2c1

InChI Key InChIKey=NGWRFPUBBONZGG-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50105566   

TargetProgesterone receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50105566(6-(3-Nitro-phenyl)-3H-benzothiazol-2-one | CHEMBL3...)
Affinity DataIC50: 84nMAssay Description:Inhibitory concentration against progesterone stimulated alkaline phosphatase activity in T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50105566(6-(3-Nitro-phenyl)-3H-benzothiazol-2-one | CHEMBL3...)
Affinity DataIC50: 84nMAssay Description:Inhibition of human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50105566(6-(3-Nitro-phenyl)-3H-benzothiazol-2-one | CHEMBL3...)
Affinity DataIC50: 326nMAssay Description:Inhibitory concentration against progesterone induced PRE-luciferase activity in CV-cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50105566(6-(3-Nitro-phenyl)-3H-benzothiazol-2-one | CHEMBL3...)
Affinity DataKi:  332nMAssay Description:Binding affinity towards progesterone receptor was measuredMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed