BDBM50108057 4'-[(3H-Imidazol-4-ylmethyl)-amino]-[1,1';2',1'']terphenyl-3-carboxylic acid 22(FTI-2195)::CHEMBL55893

SMILES OC(=O)c1cccc(c1)-c1ccc(NCc2cnc[nH]2)cc1-c1ccccc1

InChI Key InChIKey=ZUQWNRDEMRFTQP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108057   

LigandPNGBDBM50108057(4'-[(3H-Imidazol-4-ylmethyl)-amino]-[1,1';2',1'']t...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of partially purified Geranylgeranyl transferase type I (GGTase-I) from human Burkitt lymphoma (Daudi) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50108057(4'-[(3H-Imidazol-4-ylmethyl)-amino]-[1,1';2',1'']t...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of farnesyltransferase from human Burkitt lymphoma (Daudi) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed