BDBM50108116 CHEMBL3601923

SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1)-c1ccc2nc(NC(=O)NC3CC3)nn2c1

InChI Key InChIKey=YVAOMSDQXISTTH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50108116   

LigandPNGBDBM50108116(CHEMBL3601923)
Affinity DataIC50: 7nMAssay Description:Inhibition of PI3Kalpha (unknown origin) assessed as reduction of ATP level after 40 mins by luciferase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2016
Entry Details Article
PubMed
LigandPNGBDBM50108116(CHEMBL3601923)
Affinity DataIC50: 14nMAssay Description:Inhibition of PI3Kgamma (unknown origin) assessed as reduction of ATP level after 40 mins by luciferase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2016
Entry Details Article
PubMed
LigandPNGBDBM50108116(CHEMBL3601923)
Affinity DataIC50: 16nMAssay Description:Inhibition of PI3Kdelta (unknown origin) assessed as reduction of ATP level after 40 mins by luciferase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2016
Entry Details Article
PubMed
LigandPNGBDBM50108116(CHEMBL3601923)
Affinity DataIC50: 47nMAssay Description:Inhibition of PI3Kbeta (unknown origin) assessed as reduction of ATP level after 40 mins by luciferase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50108116(CHEMBL3601923)
Affinity DataIC50: 275nMAssay Description:Inhibition of mTOR (unknown origin) assessed as reduction of ATP level after 40 mins by luciferase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2016
Entry Details Article
PubMed