BDBM50109127 5-[(3-[1,4-dimethyl-6-(2-chloro-phenyl)-7,8,9,10-tetrahydro-4H-pyrido[4',3':4,5]thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-9-yl-carbonyl]-phenyl)-pyridin-3-yl-methyleneaminooxy]-pentanoic acid ethyl ester::CHEMBL323798::ethyl 5-{[1-{3-[6-(2-chlorophenyl)-1,4-dimethyl-7,8,9,10-tetrahydro-4H-pyrido[4',3':4,5]thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-9-ylcarbonyl]phenyl}-1-(3-pyridyl)-(E)-methylideneamino]-oxy}-pentanoate

SMILES CCOC(=O)CCCCO\N=C(\c1cccnc1)c1cccc(c1)C(=O)N1CCc2c(C1)sc-1c2C(=NC(C)c2nnc(C)n-12)c1ccccc1Cl

InChI Key InChIKey=GSSUDQZKNLRYQT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50109127   

TargetThromboxane-A synthase(Human)
Nikken Chemicals

Curated by ChEMBL
LigandPNGBDBM50109127(ethyl 5-{[1-{3-[6-(2-chlorophenyl)-1,4-dimethyl-7,...)
Affinity DataIC50: 65nMAssay Description:In vitro inhibition of TXB2 production by incubating prostaglandin H2 with human platelet microsomes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Nikken Chemicals

Curated by ChEMBL
LigandPNGBDBM50109127(ethyl 5-{[1-{3-[6-(2-chlorophenyl)-1,4-dimethyl-7,...)
Affinity DataIC50: 65nMAssay Description:In vitro inhibition of thromboxane synthase (TXA2) in human platelet microsomes [reduced formation of TXB2 from prostaglandin H2(PGH2)]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed