BDBM50113679 9-Isopropyl-N*6*-(3-methyl-but-2-enyl)-9H-purine-2,6-diamine::CHEMBL77155

SMILES [#6]-[#6](-[#6])-n1cnc2c(-[#7]-[#6]\[#6]=[#6](/[#6])-[#6])nc(-[#7])nc12

InChI Key InChIKey=DEEGKECYYFOKGE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50113679   

TargetCyclin-dependent kinase 1(Human)
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50113679(9-Isopropyl-N*6*-(3-methyl-but-2-enyl)-9H-purine-2...)
Affinity DataIC50: 4.50E+4nMAssay Description:Binding affinity to cyclin-dependent kinase 1 (CDK1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Human)
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50113679(9-Isopropyl-N*6*-(3-methyl-but-2-enyl)-9H-purine-2...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of cAMP-dependent protein kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50113679(9-Isopropyl-N*6*-(3-methyl-but-2-enyl)-9H-purine-2...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Cyclin A-cyclin-dependent kinase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50113679(9-Isopropyl-N*6*-(3-methyl-but-2-enyl)-9H-purine-2...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Mitogen-activated protein kinase 1 (MAPK-ERK2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 3(Human)
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50113679(9-Isopropyl-N*6*-(3-methyl-but-2-enyl)-9H-purine-2...)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of Mitogen-activated protein kinase 3 (MAPK-ERK1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50113679(9-Isopropyl-N*6*-(3-methyl-but-2-enyl)-9H-purine-2...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of Cyclin D1-cyclin-dependent kinase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed