BDBM50115863 6-Fluoro-2-[2-hydroxy-3-(pyrrolidin-3-yloxy)-phenyl]-1H-benzoimidazole-5-carboxamidine::CHEMBL61791

SMILES NC(=N)c1cc2[nH]c(nc2cc1F)-c1cccc(OC2CCNC2)c1O

InChI Key InChIKey=JTWPXAPBCSEZRE-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50115863   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50115863(6-Fluoro-2-[2-hydroxy-3-(pyrrolidin-3-yloxy)-pheny...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50115863(6-Fluoro-2-[2-hydroxy-3-(pyrrolidin-3-yloxy)-pheny...)
Affinity DataKi:  4.70E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50115863(6-Fluoro-2-[2-hydroxy-3-(pyrrolidin-3-yloxy)-pheny...)
Affinity DataKi:  5.00E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50115863(6-Fluoro-2-[2-hydroxy-3-(pyrrolidin-3-yloxy)-pheny...)
Affinity DataKi:  9.40E+4nMAssay Description:Inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50115863(6-Fluoro-2-[2-hydroxy-3-(pyrrolidin-3-yloxy)-pheny...)
Affinity DataKi:  2.25E+5nMAssay Description:Inhibition of tissue-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed