BDBM50115866 6-Fluoro-2-[2-hydroxy-3-((S)-3-methyl-cyclohexyloxy)-phenyl]-1H-benzoimidazole-5-carboxamidine::CHEMBL294067

SMILES C[C@H]1CCC[C@@H](C1)Oc1cccc(-c2nc3cc(F)c(cc3[nH]2)C(N)=N)c1O

InChI Key InChIKey=AJFFZXMHLLIFML-RYUDHWBXSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50115866   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50115866(6-Fluoro-2-[2-hydroxy-3-((S)-3-methyl-cyclohexylox...)
Affinity DataKi:  180nMAssay Description:Inhibition of urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50115866(6-Fluoro-2-[2-hydroxy-3-((S)-3-methyl-cyclohexylox...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50115866(6-Fluoro-2-[2-hydroxy-3-((S)-3-methyl-cyclohexylox...)
Affinity DataKi:  2.20E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50115866(6-Fluoro-2-[2-hydroxy-3-((S)-3-methyl-cyclohexylox...)
Affinity DataKi:  3.80E+4nMAssay Description:Inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50115866(6-Fluoro-2-[2-hydroxy-3-((S)-3-methyl-cyclohexylox...)
Affinity DataKi:  1.50E+5nMAssay Description:Inhibition of tissue-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed