BDBM50118787 2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]thiopyran-3-carboxylic acid::2-(carboxyformamido)-5,7-dihydro-4H-thieno[2,3-c]thiopyran-3-carboxylic acid::CHEMBL139423

SMILES OC(=O)C(=O)Nc1sc2CSCCc2c1C(O)=O

InChI Key InChIKey=ZPDVRWNOCOREGF-UHFFFAOYSA-N

Data  4 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50118787   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Graduate University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50118787(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]thiop...)
Affinity DataKi:  8.29E+3nMAssay Description:Binding affinity to PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Graduate University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50118787(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]thiop...)
Affinity DataKi:  8.30E+3nMpH: 5.5Assay Description:Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Graduate University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50118787(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]thiop...)
Affinity DataKi:  8.32E+3nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50118787(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]thiop...)
Affinity DataKi:  1.00E+5nMpH: 5.5Assay Description:Inhibitory effect against human protein-tyrosine phosphatase alpha (PTPalpha), using p-nitrophenyl phosphate substrate at pH 5.5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed